CONCLUSION IVL treatment modality to modify calcified lesions in the splanchnic circulation should be considered as a novel approach to patients in whom traditional endovascular treatment modalities are thought to be suboptimal. Further controlled studies are needed to access the safety, feasibility, and efficacy of the use of this novel technology in this vascular territory. BACKGROUND The experience of labour and birth is complex, multidimensional and subjective and has the potential to affect the women and their families physically and emotionally. However, there is a lack of research around maternal satisfaction in Italy. AIM To evaluate mothers' satisfaction with their childbirth experience in relation to socio-demographic characteristics, obstetric history and intrapartum care variables. METHODS A cross-sectional study involving 277 women who had given birth in a low risk maternity unit in Northern Italy was undertaken. Satisfaction with birth was measured using the Italian version of the Birth Satisfaction Scale-Revised (I-BSS-R). The scale comprises three Sub-Scales quality of care provided, personal attributes of women and stress experienced during childbirth. FINDINGS No socio-demographic variables were related to maternal satisfaction. Multiparous women had a higher satisfaction score (p=0.020; CI0.23;2.75). Antenatal class attendance was negatively associated with maternal satisfaction (p=0.038; CI-2.58; -0.07). Intrapartum variables that significantly reduced maternal satisfaction were epidural usage (p=0.000; CI-4.66; -2.07), active phase &gt;12h (p=0.000; CI-6.01; -2.63), oxytocin administration (p=0.000; CI-5.08; -2.29) and vacuum assisted birth (p=0.001; CI-6.50; -1.58). Women with an intact perineum were more likely to be satisfied (p=0.008; CI-4.60; -0.69). DISCUSSION In accordance with other research, we showed that intrapartum interventions are negatively associated with maternal outcomes and therefore also with maternal satisfaction with birth. The sub-scale that measured Quality of Care provided scored higher than the other two Sub-Scales. CONCLUSION Further studies on maternal satisfaction in Italy should be conducted, using the I-BSS-R with the aim to compare outcomes and understand what matters to women during childbirth. PROBLEM Continuity of midwifery care models are the gold standard of maternity care. Despite being recommended by the Australian Health Ministers' Advisory Council, few women in Australia have access to such models. BACKGROUND Extensive research shows that if all women had access to continuity of midwifery care, maternal and neonatal outcomes would improve. Hospital accreditation, the main national safety and quality system in Australia, aims to encourage and enable the translation of healthcare quality and safety standards into practice. AIM This paper explored the realities and possibilities of a health care accreditation system driving health service re-organisation towards the provision of continuity of midwifery care for childbearing women. METHODS A scoping review sought literature at the macro (policy) level. From 3036 records identified, the final number of sources included was 10073 research articles and eight expert opinion pieces/editorials from journals, 15 government/accreditation documents, three government/accreditation websites, and one thesis. FINDINGS Two narrative themes emerged (1) Hospital accreditation 'Here to stay' but no clear evidence and calls for change. (2) Measuring and implementing quality and safety in maternity care. DISCUSSION Regulatory frameworks drive hospitals' priorities, potentially creating conditions for change. The case for reform in the hospital accreditation system is persuasive and, in maternity services, clear. Mechanisms to actualise the required changes in maternity care are less apparent, but clearly possible. CONCLUSIONS Structural changes to Australia's health accreditation system are needed to prioritise, and mandate, continuity of midwifery care. PROBLEM In Mexico, women are often disrespected and abused during birth, evidence-based practices are seldom used, while outdated and dangerous procedures linger. BACKGROUND Disrespectful and abusive practices in Mexico have been reported but are not necessarily well-documented; none of the reports so far have relied on direct observation of births. AIM To describe birth practices and factors associated with respectful and evidence-based care at 15 referral hospitals in Mexico. METHODS We observed 401 births from 2010-2016. We analysed woman, provider, and hospital characteristics and their association with the performance of 14 evidence-based and 15 respectful birth practices via descriptive statistics and multiple logistic regression models. FINDINGS Only in four births were all the analysed evidence-based and respectful-birth practices performed. Essential interventions like uterine massage was only given to 46.1% of women and the administration of a uterotonic soon after birth only occurred in 58.3% of births. Professionals who were trained in respectful birth care were more likely to address women by their name (Odds Ratio=3.34, p less then 0.05), allow consumption of liquids during labour (Odds Ratio=31.6, p less then 0.05), encourage skin-to-skin contact (Odds Ratio=31.82, p less then 0.05), and examine the placenta after birth (Odds Ratio=16.55, p less then 0.01); they were less likely to perform episiotomies (Odds Ratio=0.27, p less then 0.05). DISCUSSION This study reveals low rates of evidence-based practices and respectful maternity care but shows training in the topic can have a considerable positive impact. Our results call for further efforts to improve the quality of maternal healthcare, a universal right. BACKGROUND Risk of melanoma is increased with potentially worse outcomes after solid organ transplant. OBJECTIVE To estimate the incidence, stage, and survival in transplant recipients with melanoma. METHODS Population-based, retrospective, observational study using linked administrative databases. Adults receiving their first solid organ transplant from 1991 through 2012 were followed to December 2013. RESULTS We identified 51 transplant recipients with melanoma, 11 369 recipients without melanoma, and 255 matched patients with melanoma from the nontransplant population. https://www.selleckchem.com/products/kpt-9274.html Transplant recipients were at increased risk of melanoma (standardized incidence ratio, 2.29; 95% confidence interval [CI], 2.07-2.49) and more likely to be diagnosed at stages II through IV (adjusted odds ratio, 4.29; 95% CI, 2.04-9.00) compared with the nontransplant population. Melanoma-specific mortality was increased in transplant recipients compared with the nontransplant population (adjusted hazard ratio, 1.93; 95% CI, 1.03-3.63). Among transplant recipients, all-cause mortality was increased after melanoma compared with those without melanoma (stage T1/T2 adjusted hazard ratio, 2.